SARS‐CoV‐2 receptor ACE2 protein expression in serum is significantly associated with age
SARS‐CoV‐2 receptor ACE2 protein expression in serum is significantly associated with age
In sum, while additional studies are needed to uncover the mechanistic basis of varying COVID‐19 clinical presentations, our data associate significantly higher ACE2 protein expression in the serum of adults compared with infants and toddlers, and in adult males compared with adult females. These data suggest the potential systemic role of ACE2 protein levels in the differential clinical manifestations among various patient populations.