Urticaria is a cutaneous mast cell-driven disease, characterized by the spontaneous development of hives and/or angioedema. Urticaria is classified as acute or chronic based on the duration of illness. In chronic urticaria (CU), signs and symptoms continue to develop for over 6 weeks with a daily or almost daily recurrence of wheals, angioedema, or both for longer than 6 weeks is defined as chronic
urticaria (CU). CU has two major subtypes, chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CINDU). CU has a greater impact on health-related quality of life (HRQoL) in pediatric patients compared to other chronic diseases of childhood.

Major current needs are specifically:
1. To trace the epidemiologic characteristics of children with CU.
2. To specify the etiology and the trigger factors to be identified with pediatric-specific focus
3.To specify the etiology as reported to doctors by parents and as reported by physicians.
4. To identify the subtypes of CU and their potential etiology in different age groups
5. The treatment algorithm needs to be further assessed for its use in children.
6. To identify the co-morbidities in children.

Aim:
1. To make a clinician survey to determine the epidemiologic characteristics of children with CU.
2. To identify the different subtypes of CU and their etiology in different age groups.
3. To trace the characteristics (etiologic, clinical, etc) of the refractory subtypes of CU.
4. To provide valuable ways to monitor new and/ or established therapeutic schemes for the management of the different subtypes of CU.
5. To provide data for the existence of any comorbidities of the different subtypes of CU. 6. To form a collaborative network looking at whether children with CU receive the appropriate level of care based on best pediatric specific evidence.