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3rd edition of the “Tell us about your project” contest

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  • Published 30/04/2025
  • Views 199

3rd edition of the “Tell us about your project” contest

Asthma Treatment with Biologics: Exploring Systemic Effects and Biomarkers for Monitoring

Speaker: Nuria Contreras

Description: Asthma is a highly prevalent chronic disease, and about 5% of patients develop severe phenotypes that are difficult to control with standard therapies. While biological drugs offer new therapeutic options, their systemic molecular effects remain poorly understood. Thus, this project aims to explore these effects to gain a deeper understanding of their underlying mechanisms and to identify potential biomarkers for treatment monitoring.

 

The Role of Major Allergens in Artemisia Pollen-Induced Asthma: Insights from a Mouse Model Study

Speaker: Nazugum Akhtemova

Description: This video presents our research on the allergenic potential of three Artemisia species using a murine asthma model. We highlight the dominant role of the major allergen Art v 1 and the predictive value of the Art v 1/Art v 3 ratio in allergic inflammation. These findings support future allergy diagnostics and vaccine development.

Understanding Anaphylaxis: How Cofactors Trigger Severe Allergic Reactions

Speaker: Blanca Raposo Martínez

Description: Why do some people have severe allergic reactions only when they exercise or take medications? This research focuses on how cofactors can intensify food allergies, especially those caused by Lipid Transfer Proteins (LTPs). Through a clinical study analyzing blood metabolites at different time points before and after exposure to specific cofactors, we aim to understand the molecular changes behind anaphylaxis and improve prevention and diagnosis for at-risk individuals.

Clinical relevance of secondary sensitizations to indoor allergens in patients with persistent allergic rhinitis in a region with high prevalence of dust mite allergy

Speaker: Daniel de Zubiria

Description: This study explored the clinical relevance of secondary sensitizations to Blomia tropicalis and pet allergens through nasal allergen challenge testing in patients with persistent allergic rhinitis primarily sensitized to house dust mites. The results revealed a lower clinical impact of B. tropicalis compared to dog and cat epithelia. Findings underscore the importance of evaluating sensitization patterns in tropical regions with high dust mite exposure.