The EAACI Guidelines provide evidence-based recommendations for your clinical practice on various topics. These are formulated by multi-disciplinary working groups with a robust methodological base, aiming to provide indications and contraindications, identifying gaps in knowledge and/ or implementation, unmet needs, and future perspectives. EAACI Guidelines are a necessary resource to homogenize clinical practice and provide the best treatment strategies for patients internationally. Read and implement them!

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    Development of guidelines

    The process of guideline development is based on the instruments ‘Grading of Recommendation, Assessment, Development and Evaluation’ (GRADE) (available at or the ‘Appraisal of Guidelines for Research and Evaluation’ (AGREE II) (available at The process requires the performance of systematic reviews according to predefined rules. EAACI guidelines embrace key opinion leaders and are usually put under the public consultation process, including the most critical stakeholders. Currently, the GRADE methodology is recommended by most experts and institutions.


    Consensus documents and position statements express the opinion elaborated by a group of opinion leaders forming a Task Force, which is approved by the EAACI ExCom and thus becomes an official position of EAACI. However, these documents do not require following the strict rules as defined for the guideline documents (see above).