Harmonization of clinical outcomes of efficacy in Food-AIT trials
Harmonization of clinical outcomes of efficacy in Food-AIT trials
Objectives: Evaluate clinical efficacy outcomes of Food AIT.Understand how the use of different outcomes can impact on the reported efficacy of food AIT trials. To identify clinical outcomes relevant for patientsProduce recommendations on what efficacy outcomes are to be used in future AIT trialsCurrent structure: In order to achieve these objectives, the work has been splitted into 3 different packages:.- WP1: Literature review to evaluate what clinical efficacy outcomes have been used so far and make a comprehensive evaluation of the pros/cons of each of them.- WP2: Assessment of the impact of using different definitions of efficacy (linked to WP 1) in a set of real patients who participated in previous peanut OIT trials.- WP3: Patient´s survey to gather patient´s input on their view of Food AIT The development of each of these WP is being done in parallel, and their results are to be interlinked in future stages. Because of the relevance and workload, each WP could constitute a dedicated TF by itself, however, it was decided that in order to optimize the team created and also to keep budget low, the 3 WP would remain as a single TF.
Pediatrics Section
Chair: Pablo Rodríguez del Río
Secretary: Montserrat Fernandez Rivas